Key paracrine interactions between glioma cells and the brain microenvironment can influence glioma pathobiology and therefore contribute to its poor prognosis. 本文讨论了目前对于通过影响肿瘤细胞和正常细胞的旁分泌作用治疗胶质瘤的方法。
MSCs naturally produce a variety of cytokines and growth factors, which are capable of promoting the survival of surrounding cells, called as paracrine effects. 间充质干细胞可以分泌多种细胞因子和生长因子，促进周围细胞的存活，发挥旁分泌作用。
